14 terms in immunology
Allergic inflammation of the nasal mucosa caused by an IgE-mediated reaction to environmental allergens (e.g., pollen, dust mites), leading …
Rare genetic disorder of lymphocyte apoptosis failure leading to chronic nonmalignant lymphoproliferation (enlarged lymph nodes & spleen) an…
Rare primary immunodeficiency (autosomal dominant) characterized by the triad of severe eczema, recurrent Staph aureus skin & lung infection…
Rare autosomal recessive immunodeficiency characterized by partial oculocutaneous albinism, recurrent pyogenic infections, and peripheral ne…
Inherited phagocyte disorder with defective NADPH oxidase. Neutrophils can't generate reactive oxygen species (like superoxide), so they can…
Primary antibody immunodeficiency with hypogammaglobulinemia (low IgG plus low IgA/IgM) causing recurrent infections and immune dysregulatio…
Gradual, controlled exposure to an allergen or drug to induce immune tolerance (reduced or eliminated hypersensitivity). In drug allergy, de…
Autosomal dominant microdeletion of chromosome 22q11.2 (usually de novo) causing defective development of the 3rd & 4th pharyngeal pouches. …
Rare autosomal dominant disorder causing deficiency or dysfunction of C1 esterase inhibitor; leads to recurrent episodes of bradykinin-media…
Primary immunodeficiency where B cells cannot class-switch, leading to normal or elevated IgM but very low IgG, IgA, IgE levels.
Inappropriate or exaggerated immune response to an antigen (allergen or self) that causes host tissue damage; classically categorized into f…
A group of rare inherited immunodeficiencies characterized by profound T- and B-cell dysfunction, leading to extreme vulnerability to infect…
Inflammation of the uveal tract (iris, ciliary body, choroid). Anterior uveitis (iritis/iridocyclitis) affects the iris and ciliary body; in…
X-linked recessive immunodeficiency caused by a BTK gene mutation, resulting in failure of B cell maturation and near-absent immunoglobulins…